Vinflunine ditartrate

CAS: 194468-36-5

Ref. 3D-FV28698

Produktinformation

• Name: Vinflunine ditartrate
• Synonyme: 4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine ditartrate20',20'-Difluoro-3',4'-dihydrovinorelbine ditartrateBMS 710485, 20',20'-Difluoro-3',4'-dihydrovinorelbine Ditartrate, 4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine Ditartrate, Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (salt), Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12β,19α)-, (2R,3R)-2,3-dihydroxybutanedioate (1:2), Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(2R,4R,6S,8S)-4-(1,1-difluoroethyl)-1,3,4,5,6,7,8,9-octahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12β,19α)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:2) (salt), Bms 710485, Javlor, Vinflunine Ditartrate, F 12158

Beschreibung

Vinflunine is a cytotoxic drug that inhibits the polymerization of actin and prevents cell division. It binds to the terminal amino group of lysine residues on the side chain of actin monomers, preventing polymerization and thus inhibiting cell division. Vinflunine has been shown to be effective against solid tumours such as prostate cancer cells or bladder cancer cells, which are resistant to chemotherapy. Vinflunine also has an antineoplastic effect by inhibiting the proliferation of cancer cells. There are two forms of vinflunine: a ditartrate salt (vinflunine ditartrate) and a hydrogen fluoride salt (vinflunine hydrogen fluoride). The molecular weight of vinflunine ditartrate is 477.6 g/mol and its IUPAC name is 2-[(2H-1,2-benzothiazol-3(2H)-on-5-yl

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 1,117.1 g/mol
• Formel: C₅₃H₆₆F₂N₄O₂₀
• Reinheit: Min. 95%
• Farbe/Form: Off-White Powder