Pyropheophorbide a methyl ester

CAS: 6453-67-4

Ref. 3D-GAA45367

Produktinformation

• Name: Pyropheophorbide a methyl ester
• Synonyme: 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S,4S)-, Pyrophaeophorbide-a-monomethyl ester, Methyl 4-(9-Ethenyl-14-Ethyl-4,8,13-Trimethyl-20-Oxophorbin-3-Yl)Butanoate, Methyl 3-(9-Ethenyl-14-Ethyl-4,8,13,18-Tetramethyl-20-Oxo-24,25-Dihydrophorbin-3-Yl)Propanoate, Methyl pyropheophorbide-a

Beschreibung

Pyropheophorbide a methyl ester is an organic compound that is used in photodynamic therapy. It binds to hemoglobin, which is the oxygen-carrying protein of red blood cells. The binding of pyropheophorbide a methyl ester to hemoglobin causes it to become unstable and break down into reactive molecules that are cytotoxic. The carbonyl group on this molecule also makes it a good substrate for ABCG2, which is a transporter protein found on the surface of cancer cells. This drug has shown success in treating prostate cancer cells and herpes simplex virus. Pyropheophorbide a methyl ester has been shown to produce tumour necrosis when irradiated with UVB light, by inducing apoptosis and inducing the production of reactive oxygen species.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 548.67 g/mol
• Formel: C₃₄H₃₆N₄O₃
• Reinheit: Min. 95%