Produktinformation
3-Hydroxy-3-phenylpentanamide is a chiral molecule that has been found to produce neurotoxic effects in rats. 3-Hydroxy-3-phenylpentanamide binds to the benzodiazepine binding site on the GABA receptor and produces a neurotoxic effect. The neurotoxicity of this drug was studied using x-ray crystallography and it was found that 3-hydroxy-3-phenylpentanamide binds with high affinity to the gamma amino butyric acid (GABA) receptor, which causes an increase in chloride ion flow into the neuron and can lead to death of the neuron. This compound also has a halogen substituent at C3, which may be responsible for its toxicity. 3-Hydroxy-3-phenylpentanamide is an enantiomer that is not present in nature and is produced synthetically by reacting phenylacetonitrile with hydroxylamine followed by chlorination. It has
Chemische Eigenschaften
Technische Anfrage zu: 3D-GFA80269 3-Hydroxy-3-phenylpentanamide
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