1-Oxo-1,2-dihydroisoquinoline-3-carboxylic acid

CAS: 7509-13-9

Ref. 3D-HAA50913

Produktinformation

• Name: 1-Oxo-1,2-dihydroisoquinoline-3-carboxylic acid
• Synonyme: 1,2-Dihydro-1-oxo-3-isoquinolinecarboxylic acid, 1-Hydroxyisoquinoline-3-carboxylic acid, 3-Isoquinolinecarboxylic Acid, 1,2-Dihydro-1-Oxo-, Isocarbostyril-3-carboxylic acid, NSC 131339, NSC 407253

Beschreibung

1-Oxo-1,2-dihydroisoquinoline-3-carboxylic acid (ODHC) is a synthetic compound that has been shown to have anti-tumor activity in mouse melanoma cells. ODHC inhibits the production of aldehydes through the interaction with thiourea and homophthalic acid. ODHC also binds to topoisomerase II, which prevents the unwinding of DNA and limits DNA replication. This leads to cell death by inhibition of DNA synthesis. ODHC has been shown to be photostable and has a low toxicity for healthy cells. It is also able to chelate metal ions, such as iron, copper, or zinc, which are important for cancer cell growth and proliferation.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 189.17 g/mol
• Formel: C₁₀H₇NO₃
• Reinheit: Min. 95%