5(S),6(R)-Dihydroxy-7(E),9(E),11(Z),14(Z)-eicosatetraenoic acid

CAS: 82948-88-7

Ref. 3D-HDA94888

Produktinformation

• Name: 5(S),6(R)-Dihydroxy-7(E),9(E),11(Z),14(Z)-eicosatetraenoic acid

Beschreibung

5(S),6(R)-Dihydroxy-7(E),9(E),11(Z),14(Z)-eicosatetraenoic acid (5,6-DHETE) is a metabolite of arachidonic acid. It is formed by the action of cytosolic 5-lipoxygenase on arachidonic acid and functions as an intermediate in the synthesis of leukotriene A4. This metabolite has been shown to induce chemotaxis of human leukocytes. 5,6-DHETE has also been shown to be a substrate for epoxide hydrolase and epoxide reductase, which converts it to its corresponding alcohols, 5,6-dihydroxyeicosatrienoic acid and 7,9,11,14-tetrahydroxyeicosatrienoic acid respectively. The enzyme epoxide hydrolase can be

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 336.5 g/mol
• Formel: C₂₀H₃₂O₄
• Reinheit: Min. 95%