3-(1,3-oxazol-5-yl)aniline

CAS: 157837-31-5

Ref. 3D-HGA83731

Produktinformation

• Name: 3-(1,3-oxazol-5-yl)aniline
• Synonyme: 5-(3-Aminophenyl)Oxazole, Buttpark 43\57-51

Beschreibung

3-(1,3-Oxazol-5-yl)aniline is an inhibitor of the enzyme phosphoglycerate dehydrogenase (PGDH), which catalyzes the oxidation of 2-phosphoglycerate to 3-phosphoglycerate. It binds to PGDH and slows down the formation of 3-phosphoglycerate, which inhibits the production of ATP. The binding site for 3-(1,3-oxazol-5-yl)aniline has been determined by X-ray crystallography and affinity measurements to be near a conserved amino acid residue in the active site. This inhibition prevents cancer cells from growing and dividing. 3-(1,3-Oxazol-5-yl)aniline has been shown to inhibit breast cancer cells in vitro with high affinity.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 160.17 g/mol
• Formel: C₉H₈N₂O
• Reinheit: Min. 95%