PF 04447943

CAS: 1082744-20-4

Ref. 3D-HTB74420

Produktinformation

• Name: PF 04447943
• CAS: 1082744-20-4

Beschreibung

PF 04447943 is a small-molecule, orally bioavailable drug with potential for the treatment of inflammatory bowel disease (IBD). PF 04447943 is a potent inhibitor of TNF-α, which is involved in the pathogenesis of IBD. This compound has been shown to have statistically significant efficacy in wild-type mice and to have low expression in human nuclear DNA. The onset latency of this drug is approximately one week. PF 04447943 inhibits NF-κB and other signal pathways that are involved in the inflammatory response. It also inhibits glutamate dehydrogenase and has shown activity against natural compounds in vitro.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 395.46 g/mol
• Formel: C₂₀H₂₅N₇O₂
• Reinheit: Min. 95%