FRAX486

CAS: 1232030-35-1

Ref. 3D-HZB03035

Produktinformation

• Name: FRAX486
• Synonyme: 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one
• CAS: 1232030-35-1

Beschreibung

FRAX486 is a kinase inhibitor that binds to the ATP-binding site of the epidermal growth factor receptor (EGFR) and prevents it from binding to ATP. The EGFR is involved in signaling pathways that are important for cell proliferation, differentiation, and survival. FRAX486 is selective for EGFR over other members of the tyrosine kinase family, such as CDK4/6. This drug has been shown to inhibit tumor growth by inducing apoptosis in mutant melanoma cells and inhibiting their migration. It also inhibits the phosphorylation of actin filaments and reduces bladder inflammation.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 513.4 g/mol
• Formel: C₂₅H₂₃Cl₂FN₆O
• Reinheit: Min. 95%