Acyclovir acetate

CAS: 102728-64-3

Ref. 3D-IA17213

Produktinformation

• Name: Acyclovir acetate
• Synonyme: 9-[[2-(Acetyloxy)ethoxy]methyl]-2-amino-1,9-dihydro-6H-purin-6-one9-(2-Acetoxyethoxymethyl)guanineAcyclovir Impurity A
• Marke: Biosynth

Beschreibung

Acyclovir is an antiviral agent that prevents the growth of herpes simplex virus. Acyclovir is a prodrug, which is converted to acycloguanosine 5'-triphosphate (ACV-TP) in vivo. ACV-TP inhibits viral DNA polymerase and thereby prevents viral genome replication, replication. The molecular structure of Acyclovir was determined by X-ray crystallography at 3.2 Å resolution. It has been shown that ACV-TP can be activated by chloride ions and it has been suggested that this activation may be the result of an interaction with a ligand.
ACV-TP binds to guanine residues in the DNA chain and prevents the formation of hydrogen bonds between guanine and adenine or cytosine residues in the same chain, preventing DNA replication.

Chemische Eigenschaften

• Molekulargewicht: 267.24 g/mol
• Formel: C₁₀H₁₃N₅O₄
• Reinheit: Min. 95%
• Farbe/Form: White Powder
• InChl: InChI=1S/C10H13N5O4/c1-6(16)19-3-2-18-5-15-4-12-7-8(15)13-10(11)14-9(7)17/h4H,2-3,5H2,1H3,(H3,11,13,14,17)
• InChI Key: InChIKey=DMHAXLGAKQREIL-UHFFFAOYSA-N
• SMILES: CC(=O)OCCOCn1cnc2c(=O)[nH]c(N)nc21