13-O-Desmethyl tacrolimus

CAS: 139958-51-3

Ref. 3D-ID161984

Produktinformation

• Name: 13-O-Desmethyl tacrolimus

Beschreibung

Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 789.99 g/mol
• Formel: C₄₃H₆₇NO₁₂
• Reinheit: 90%Min
• Farbe/Form: Powder