Praeruptorin C

CAS: 83382-71-2

Ref. 3D-IDA38271

Produktinformation

• Name: Praeruptorin C
• Synonyme: 2-Butenoic acid, 2-methyl-, (9R,10R)-9,10-dihydro-8,8-dimethyl-10-(3-methyl-1-oxobutoxy)-2-oxo-2H,8H-benzo[1,2-b:3,4-b′]dipyran-9-yl ester, (2Z)-, 2-Butenoic acid, 2-methyl-, 9,10-dihydro-8,8-dimethyl-10-(3-methyl-1-oxobutoxy)-2-oxo-2H,8H-benzo[1,2-b:3,4-b′]dipyran-9-yl ester, [9R-[9α(Z),10α]]-, 2H,8H-Benzo[1,2-b:3,4-b′]dipyran, 2-butenoic acid deriv., Wulongensin A
• CAS: 83382-71-2

Beschreibung

Praeruptorin C is a natural compound that inhibits the transcriptional activity of RNA polymerase. It has been shown to lower systolic pressure in mice and rats by inhibiting the accumulation of cytosolic Ca2+ in ventricular myocardium cells. Praeruptorin C also has a protective effect on cardiac muscle cells, which may be due to its ability to inhibit the accumulation of Ca2+. This compound also has a number of toxicological studies, making it suitable for use in clinical trials. Praeruptorin C is water-soluble and can be administered orally or intravenously. It is metabolized by hydrolysis into glycol esters and coumarins derivatives. The pharmacokinetics study showed that after oral administration, praeruptorin C was rapidly absorbed and eliminated from the body with an elimination half-life of about 2 hours.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 428.5 g/mol
• Formel: C₂₄H₂₈O₇
• Reinheit: Min. 95%