E-64

CAS: 66701-25-5

Ref. 3D-IES-4096-V

Produktinformation

• Name: E-64
• Synonyme: [(2S,3S)-3-Carboxyoxirane-2-carbonyl]-L-leucine (4-guanidinobutyl)amide L-trans-Epoxysuccinyl-Leu-4-guanidinobutylamide L-trans-Ep oxysuccinyl-Leu-agmatine
• Marke: Biosynth
• Beschreibung: E-64 is a research tool that is used to study protein interactions. It has been shown to inhibit ion channels, such as the nicotinic acetylcholine receptor and the voltage-gated calcium channel. E-64 binds to receptors in the cell membrane, blocking ion channels and altering intracellular signaling pathways. E-64 has been shown to inhibit nitric oxide synthase, which may account for its anti-inflammatory properties. E-64 also inhibits an enzyme called protein tyrosine phosphatase 1B (PTP1B), which is involved in insulin resistance and type 2 diabetes mellitus.

Chemische Eigenschaften

• Molekulargewicht: 357.41 g/mol
• Formel: C₁₅H₂₇N₅O₅
• Reinheit: Min. 95%