11-Fluoro desloratadine

CAS: 298220-99-2

Ref. 3D-IF46257

Produktinformation

• Name: 11-Fluoro desloratadine
• Synonyme: Desloratadine impurity A8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• Marke: Biosynth
• Beschreibung: 11-Fluoro desloratadine is a metabolite of the antihistamine, loratadine. It has shown to be an analytical standard for HPLC, and impurity standard for pharmacopoeia. 11-Fluoro desloratadine is typically synthesized by reacting loratadine with fluorinating reagent such as N-fluorosuccinimide (NFSI) in the presence of a base catalyst such as sodium methoxide. 11-Fluoro desloratadine is also found in breast milk at concentrations of up to 1.2% of total loratadine concentration, which has been attributed to incomplete metabolism or passive transfer from mother to child.

Chemische Eigenschaften

• Molekulargewicht: 330.83 g/mol
• Formel: C₁₉H₂₀N₂ClF
• Reinheit: Min. 95%
• Farbe/Form: Powder