Nevanimibe hydrochloride

CAS: 133825-81-7

Ref. 3D-IFA82581

Produktinformation

• Name: Nevanimibe hydrochloride
• Synonyme: N-[2,6-Bis(1-methylethyl)phenyl]-N′-[[1-[4-(dimethylamino)phenyl]cyclopentyl]methyl]urea hydrochloride, ATR 101, Urea, N-[2,6-bis(1-methylethyl)phenyl]-N′-[[1-[4-(dimethylamino)phenyl]cyclopentyl]methyl]-, hydrochloride (1:1), Urea, N-[2,6-bis(1-methylethyl)phenyl]-N′-[[1-[4-(dimethylamino)phenyl]cyclopentyl]methyl]-, monohydrochloride, PD 132301-2

Beschreibung

Nevanimibe is a non-steroidal androgen that has been shown to reduce the size of the adrenal glands. It inhibits 17-hydroxylase activity and prevents the synthesis of 17-hydroxyprogesterone, which is a mineralocorticoid. Nevanimibe also inhibits cellular hypertrophy, an endpoint in clinical laboratory tests. In vitro studies have shown nevanimibe to be effective against adrenocortical carcinoma cells and to inhibit their growth. The drug has been found to be active against some strains of Staphylococcus aureus, but not against Mycobacterium tuberculosis or other acid-fast bacteria.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 458.1 g/mol
• Formel: C₂₇H₄₀ClN₃O
• Reinheit: Min. 95%