4-Keto 13-cis-retinoic acid

CAS: 71748-58-8

Ref. 3D-IK24759

Produktinformation

• Name: 4-Keto 13-cis-retinoic acid
• Synonyme: 3,7-Dimethyl-9-(4-keto-2,6,6-trimethyl-1-cyclohexen-1-yl)-2Z,4E,6E,8E-nonatetranenoic acid4-OxoisotretinoinIsotretinoin impurity H, 13-cis-4-Oxoretinoic acid, Retinoic acid, 4-oxo-, 13-cis-, 4-Oxoisotretinoin, Ro 22-6595

Beschreibung

4-Keto 13-cis-retinoic acid is a synthetic retinoid that was first synthesized in the 1970s. It is used for the treatment of ichthyosiform erythroderma and other skin diseases. 4-Keto 13-cis-retinoic acid binds to the retinoic acid receptor, which may be responsible for its effects on epidermal growth factor and cytosolic calcium. Treatment with 4-keto 13-cis-retinoic acid has been shown to inhibit the proliferation of hl-60 cells and squamous carcinoma cells in vitro, as well as reduce tumor size and metastasis in vivo. >>END

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 314.42 g/mol
• Formel: C₂₀H₂₆O₃
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C20H26O3/c1-14(7-6-8-15(2)13-19(22)23)9-10-17-16(3)18(21)11-12-20(17,4)5/h6-10,13H,11-12H2,1-5H3,(H,22,23)/b8-6+,10-9+,14-7+,15-13-
• InChI Key: InChIKey=GGCUJPCCTQNTJF-FAOQNJJDSA-N
• SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C\C(=O)O)C(C)(C)CCC1=O