Mitoxantrone (2-hydroxyethyl)piperazine impurity

CAS: 137132-70-8

Ref. 3D-IM26023

Produktinformation

• Name: Mitoxantrone (2-hydroxyethyl)piperazine impurity
• Synonyme: 1,2,3,4-Tetrahydro-8,11-dihydroxy-4-(2-hydroxyethyl)-6-[[2-[(2-hydroxyethyl)amino]ethyl]amino]naphtho[2,3-f]quinoxaline-7,12-dioneM itoxantrone impurity D
• Marke: Biosynth
• Beschreibung: Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.

Chemische Eigenschaften

• Molekulargewicht: 442.47 g/mol
• Formel: C₂₂H₂₆N₄O₆
• Reinheit: Min. 95%
• Farbe/Form: Brown Powder
• InChl: InChI=1S/C22H26N4O6/c27-9-6-23-3-4-24-12-11-13-20(25-5-7-26(13)8-10-28)19-16(12)21(31)17-14(29)1-2-15(30)18(17)22(19)32/h1-2,11,23-25,27-30H,3-10H2
• InChI Key: InChIKey=GJMHXLAWJIOZMT-UHFFFAOYSA-N
• SMILES: O=C1c2c(O)ccc(O)c2C(=O)c2c3c(cc(NCCNCCO)c21)N(CCO)CCN3