Olanzapine N-oxide

CAS: 174794-02-6

Ref. 3D-IO106348

Produktinformation

• Name: Olanzapine N-oxide
• Synonyme: Olanzapine impurity 4Olanzapine impurity D, Ly 170238, 2-Methyl-4-(4-methyl-4-oxido-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-4-oxidopiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine

Beschreibung

Olanzapine N-oxide is a metabolite of olanzapine. It is produced by the oxidative deamination of olanzapine, which is catalyzed by cytochrome P450 enzymes. Olanzapine N-oxide has been shown to be responsible for some of the side effects associated with olanzapine, such as weight gain and sedation. The presence of olanzapine N-oxide in human plasma has been shown to increase with age and in women, which may be due to its higher affinity for α1-acid glycoprotein. Olanzapine N-oxide can be detected in urine or faeces using gas chromatography/mass spectrometry (GC/MS) or liquid chromatography with tandem mass spectrometry (LC/MS).

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 328.43 g/mol
• Formel: C₁₇H₂₀N₄OS
• Reinheit: Min. 95%
• Farbe/Form: Powder