Simvastatin hydroxy acid ethyl ester

CAS: 864357-87-9

Ref. 3D-IS27836

Produktinformation

• Name: Simvastatin hydroxy acid ethyl ester
• Synonyme: (b-R,?R,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-b,?-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic acid ethyl ester

Beschreibung

Simvastatin hydroxy acid ethyl ester is a solvated form of simvastatin, an investigational drug for the treatment of dyslipidemia. The ammonium salt was prepared by alcoholysis with ethanol. The elution process was carried out using an acetonitrile-water mixture and chromatography on silica gel. Preparation methods were investigated to determine the best preparative procedure that would yield pure material. This compound has been investigated as a possible therapeutic agent for the treatment of midbody diseases such as familial amyloidotic polyneuropathy and Alzheimer's disease.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 464.63 g/mol
• Formel: C₂₇H₄₄O₆
• Reinheit: Min. 95%
• Farbe/Form: Colourless To Pale Yellow Liquid