Camostat Mesilate

CAS: 59721-29-8

Ref. 3D-ISP-3606-PI

Produktinformation

• Name: Camostat Mesilate
• Marke: Biosynth
• Beschreibung: Camostat mesilate is a prodrug that is metabolized to the active form, pemastatin. It is used for the treatment of bowel disease and squamous cell carcinoma. Camostat mesilate inhibits the TNF-α receptor by binding to its response element in vitro and in vivo. The biological properties of camostat mesilate are due to its ability to inhibit TNF-α production by binding to the TNF-α receptor, thereby preventing activation of transcription factors such as nuclear factor kappa B (NFκB). In vitro assays have shown that camostat mesilate induces apoptosis in human carcinoma cell lines through inhibition of growth factor-β1. This drug has also been shown to be effective in treating viral infections, including HIV and herpes zoster.

Chemische Eigenschaften

• Molekulargewicht: 494.5 g/mol
• Formel: C₂₀H₂₂N₄O₅•CH₃SO₃H
• Reinheit: Min. 95%