Teriflunomide

CAS: 163451-81-8

Ref. 3D-J-010046

Produktinformation

• Name: Teriflunomide
• Synonyme: A 771726 N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotoamide
• Marke: Biosynth
• Beschreibung: Teriflunomide is a drug that has been clinically proven for the treatment of multiple sclerosis. It is a prodrug that is converted to its active form, teriflunomide-phosphate, in vivo. Teriflunomide inhibits the activity of matrix metalloproteinases by blocking Ca2+ channels and inhibiting Ca2+ influx into the cytosol. This blocks the degradation of extracellular matrix proteins and reduces inflammation, which may lead to long-term efficacy in autoimmune diseases such as multiple sclerosis. Teriflunomide also decreases T-cell proliferation by inhibiting integrin receptors on T cells and monoclonal antibody production.

Chemische Eigenschaften

• Molekulargewicht: 270.21 g/mol
• Formel: C₁₂H₉F₃N₂O₂
• Reinheit: Min. 98 Area-%