1-Benzyl-5-bromo-1H-indole

CAS: 10075-51-1

Ref. 3D-KAA07551

Produktinformation

• Name: 1-Benzyl-5-bromo-1H-indole
• Synonyme: 1-Benzyl-5-Bromoindole, 1H-Indole, 5-bromo-1-(phenylmethyl)-, 5-Bromo-1-(phenylmethyl)-1H-indole, Indole, 1-benzyl-5-bromo-, N-Benzyl-5-bromoindole, NSC 143237
• CAS: 10075-51-1

Beschreibung

1-Benzyl-5-bromo-1H-indole is an indole that reacts with metallation to produce 1,2,3,4-tetrahydroquinoline. This reaction can be done in the presence of a base such as sodium methoxide or potassium tert-butoxide and a metal halide such as copper(I) bromide or silver(I) bromide. It was isolated in yields of 25% from the reaction of 5-bromoindole with benzaldehyde. The syntheses of isatins and their analogs have been accomplished by carbonylation of indoles with phosporane and alcohols in the presence of aluminum chloride. In this way, 1-(2'-chlorobenzyl)-5-(trifluoromethyl)indole was obtained.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 286.17 g/mol
• Formel: C₁₅H₁₂BrN
• Reinheit: Min. 95%