Febuxostat Sec-butoxy acid

CAS: 1335202-59-9

Ref. 3D-KDC20259

Produktinformation

• Name: Febuxostat Sec-butoxy acid
• Marke: Biosynth
• Beschreibung: Febuxostat is a non-peptide inhibitor of xanthine oxidase (XO), an enzyme that catalyzes the conversion of xanthine and hypoxanthine to uric acid. Febuxostat is used as a treatment for chronic gout in adults who are not adequately controlled on allopurinol alone or who cannot tolerate allopurinol. Febuxostat has been shown to be effective in inhibiting the activity of human recombinant XO, both in vitro and in vivo. The compound is a competitive inhibitor of L-histidine with an IC50 of 0.3 microM at pH 7.4 and 0.1 microM at pH 6.0, which is more potent than other peptidomimetics such as febuprofen and fexofenadine, but less potent than CGP57148B and CGP37849A.Febuxostat has also been shown to have

Chemische Eigenschaften

• Molekulargewicht: 316.4 g/mol
• Formel: C₁₆H₁₆N₂O₃S
• Reinheit: Min. 95%