5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one

CAS: 311795-38-7

Ref. 3D-LMA79538

Produktinformation

• Name: 5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one

Beschreibung

5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one (TZT) is an experimental drug that inhibits glutaminase and is used to treat cancer. It has been shown to inhibit the growth of human epidermal growth factor receptor 2 (HER2), mda-mb231 breast cancer cells and human CD4+ lymphocytes. TZT also inhibits the production of glutamine in cancer cells. This inhibition leads to a decrease in the synthesis of proteins and DNA, which may lead to apoptosis or cell death. TZT has been shown to be effective against a number of carcinoma cell lines including cervical cancer and is not toxic for normal cells such as fetal bovine serum or healthy skin fibroblasts.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 475.42 g/mol
• Formel: C₂₇H₂₇BrN₂O
• Reinheit: Min. 95%