Acetaminophen D-glucuronide

CAS: 16110-10-4

Ref. 3D-MA09392

Produktinformation

• Name: Acetaminophen D-glucuronide
• Synonyme: Paracetamol-O-D-glucuronidep-Acetylaminophenol-O-D-glucuronide
• Marke: Biosynth
• Beschreibung: Acetaminophen D-glucuronide (APG) is a metabolite of acetaminophen. It is a major metabolite produced by the liver after acetaminophen is converted to APG by UDP-glucuronyltransferase. The biological properties of APG are similar to acetaminophen, but it has been shown that APG may have greater potency than acetaminophen in some tissues. For example, in vitro studies using hepatocyte-like cells have shown that APG has higher activity than acetaminophen on the induction of CYP2E1 and CYP3A4, two enzymes involved in drug metabolism. Acetaminophen D-glucuronide can be detected in blood samples for up to 48 hours after administration of an intravenous dose of acetaminophen, which provides a more precise measurement than other methods such as plasma concentrations or urinary excretion measurements.

Chemische Eigenschaften

• Molekulargewicht: 327.29 g/mol
• Formel: C₁₄H₁₇NO₈
• Reinheit: Min. 95%
• Farbe/Form: White Powder