7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid

CAS: 128885-13-2

Ref. 3D-MD59582

Produktinformation

• Name: 7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid
• Synonyme: 3,5-Dideoxy-5-((hydroxyacetyl)amino)-8-O-methyl-D-glycero-D-galacto-2-nonulosonic acid 7,9-diacetate, 8-O-Me-7,9-di-O-Nac-gcneu, Mafn, D-glycero-D-galacto-2-Nonulosonic acid, 3,5-dideoxy-5-((hydroxyacetyl)amino)-8-O-methyl-, 7,9-diacetate, 7,9-di-O-acetyl-3,5-dideoxy-5-[(hydroxyacetyl)amino]-8-O-methyl-D-glycero-D-galacto-non-2-ulosonic acid

Beschreibung

7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid is a synthetic glycolylneuraminic acid analogue that can be used in the treatment of bacterial infections. It is a prodrug that is converted to glycolylneuraminic acid by monoclonal antibody and other enzymes. 7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid inhibits the activity of necrosis factor (TNF) by binding to its receptor, thereby preventing TNF from binding to cells and stimulating inflammation. This compound has been shown to be effective against many bacteria including methicillin resistant Staphylococcus aureus (MRSA). Techniques used for the synthesis include high performance liquid chromatography with mass spectrometry detection and cavity ring down spectroscopy.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 423.37 g/mol
• Formel: C₁₆H₂₅NO₁₂
• Reinheit: Min. 95%