Seletalisib (UCB-5857)

CAS: 1362850-20-1

Ref. 3D-MEC85020

Produktinformation

• Name: Seletalisib (UCB-5857)
• CAS: 1362850-20-1

Beschreibung

Seletalisib is a novel, potent, and selective inhibitor of the lipid kinase activity. It blocks protein synthesis by binding to the ribosomal protein S6 kinase-1 (RSK1) which is involved in regulating cell proliferation and differentiation. Seletalisib has been shown to be effective in clinical studies for treatment of autoimmune diseases such as systemic lupus erythematosus (SLE). This drug also has pharmacokinetic properties that are suitable for hepatic impairment. Seletalisib also inhibits the production of chemokines, which are inflammatory cytokines that induce chemotaxis of leukocytes and promote inflammation.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 482.85 g/mol
• Formel: C₂₃H₁₄ClF₃N₆O
• Reinheit: Min. 95%