L-Glycero-D-manno-heptose

CAS: 4305-74-2

Ref. 3D-MG04722

Produktinformation

• Name: L-Glycero-D-manno-heptose
• Synonyme: glycero-manno-Heptose, D-glycero-D-manno-Heptose

Beschreibung

L-Glycero-D-manno-heptose is a polymyxin B antimicrobial agent that has been shown to have significant activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae. This compound also has an inhibitory effect on the growth of Gram-negative species such as Salmonella enterica. L-Glycero-D-manno-heptose inhibits the synthesis of bacterial cell wall peptidoglycan by binding to the terminal residues of oligosaccharides, which are linked to D-alanine in the peptidoglycan chain. The terminal residues of oligosaccharides are transferred from the lipid carrier to L-glycero-D manno heptose, forming a stable acylated glycoside. This reaction mechanism is similar to that of polymyxin B, but with a difference in reactivity due to steric hindrance.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 210.18 g/mol
• Formel: C₇H₁₄O₇
• Reinheit: Min. 95%
• Farbe/Form: White Powder