Nefopam glucuronide

Ref. 3D-MN46697

Produktinformation

• Name: Nefopam glucuronide
• Synonyme: Nefopam N-b-D glucuronide

Beschreibung

Nefopam is a compound that has been used as an analgesic and antipyretic. It is structurally related to the benzodiazepine class of drugs, but is not chemically equivalent to any other known drug. Nefopam has a low therapeutic index and can cause severe toxic effects in overdose. The most common adverse effects of nefopam are dizziness, drowsiness, headache, nausea and vomiting. An overdose can lead to death by respiratory paralysis or cardiac arrest.

Nefopam glucuronide is the major metabolite of nefopam in humans and animals. It is formed by the conjugation of nefopam with glucuronic acid in liver cells. Nefopam glucuronide has no analgesic properties but some sedative properties. The blood concentration of nefopam glucuronide is proportional to the dose administered; however, it does not correlate well with clinical effects because it does not cross the

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 429.46 g/mol
• Formel: C₂₃H₂₇NO₇
• Reinheit: Min. 95%