Salicylic acid D-glucuronide

CAS: 7695-70-7

Ref. 3D-MS09950

Produktinformation

• Name: Salicylic acid D-glucuronide
• Synonyme: 2-Carboxyphenyl b-D-glucopyranosiduronic acid, 2-Carboxyphenyl β-D-glucopyranosiduronic acid, Glucopyranosiduronic acid, o-carboxyphenyl, β-D-, β-D-Glucopyranosiduronic acid, o-carboxyphenyl, Salicyl phenolic glucuronide, β-D-Glucopyranosiduronic acid, 2-carboxyphenyl

Beschreibung

Salicylic acid D-glucuronide is the major metabolite of aspirin, which is formed by hydrolysis of acetylsalicylic acid. It has been demonstrated to have anti-inflammatory and analgesic effects. Salicylic acid D-glucuronide is excreted in urine and can be detected in human serum. The formation rate of this metabolite varies with the individual's age, sex, and kidney function.
Salicylic acid D-glucuronide can be formed in vitro using hydrochloric acid and acetylsalicylic acid as substrates. This reaction is catalyzed by the enzyme uridine diphosphate glucuronyltransferase (UGT). Salicylic acid D-glucuronide has been shown to form covalent adducts with hydroxyl groups from other molecules in vivo and in vitro, including proteins (e.g., albumin) and DNA bases (e.g.,

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 314.24 g/mol
• Formel: C₁₃H₁₄O₉
• Reinheit: Min. 95%
• Farbe/Form: Powder