1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose

CAS: 68733-20-0

Ref. 3D-MT07137

Produktinformation

• Name: 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose
• Synonyme: 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-alpha-D-mannopyranose, 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose

Beschreibung

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-a-D-mannopyranose (1,3,4,6-TA) is a stable analog of the glycosidic sugar 2,6-dideoxymannose. This compound has been shown to be a potent inhibitor of the synthesis of Neisseria meningitidis capsular polysaccharides and an effective vaccine adjuvant against Mycobacterium tuberculosis. 1,3,4,6-TA is also a competitive inhibitor for the enzyme mycothiol and other thioglycosidic enzymes that are involved in the biosynthesis of mycolic acids. 1,3,4,6-TA was synthesized from 2-(N'-bromoacetamido)-2'-deoxymannose by reaction with sodium azide in acetone. The structure is bicyclic with two

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 373.32 g/mol
• Formel: C₁₄H₁₉N₃O₉
• Reinheit: Min. 95%
• Farbe/Form: White Powder