Telmisartan acyl-b-D-glucuronide

CAS: 250780-40-6

Ref. 3D-MT07380

Produktinformation

• Name: Telmisartan acyl-b-D-glucuronide
• Synonyme: 1-[4'-[(1',4-Dimethyl-2-propyl[2'-propyl[2',6-b1-1H-benzimdazol]-1-yl)methyl)][1,1'-biphenyl]-2-carboxylate]-b-D-glucopyranuronic ac id
• Marke: Biosynth
• Beschreibung: Telmisartan acyl-b-D-glucuronide is a drug metabolite that is formed by the conjugation of telmisartan with glucuronic acid. Telmisartan acyl-b-D-glucuronide is activated in vivo and reversibly inhibits the enzyme creatine kinase, which is involved in the metabolism of creatine to creatinine. The effective dose for this compound has been shown to be 10 mg/kg (orally) in humans. Telmisartan acyl-b-D-glucuronide has been shown to be an at1 receptor antagonist and may have some antihypertensive effects via modulation of ion channels. This drug also appears to have some proliferative effects on cells that are inhibited by radiation.

Chemische Eigenschaften

• Molekulargewicht: 690.74 g/mol
• Formel: C₃₉H₃₈N₄O₈
• Reinheit: Min. 95%
• Farbe/Form: Off-White Powder