Tri-b-GalNAc-C12-amido-C3-azide

Ref. 3D-MT184242

Produktinformation

• Name: Tri-b-GalNAc-C12-amido-C3-azide
• Synonyme: Tris-β-GalNAc-C12-azideTrebler GalNAc azidetris-GalNAc-C12-3-azidopropylamine3-azidopropylamino-C12-tris-beta-GalNAc

Beschreibung

Tri-b-GalNAc-C12-amido-C3-azide is a unique bifunctional ligand for ASGPR-targeted applications. The three terminal GalNAc sugars can bind to ASGPR receptors that permit hepatocyte uptake, the C12-amide linker offers a stable spacer and the C3-azide moiety enables tailored bioconjugation via CuAAC click chemistry. This design has the potential for targeted delivery of therapeutic cargo (drugs, siRNA, nanoparticles) to hepatocytes, development of LYTACs for selective protein degradation, and creation of in vivo ASGPR imaging probes.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 1,709.97 g/mol
• Formel: C₇₆H₁₃₆N₁₄O₂₉
• Reinheit: Min. 95%