Tri-b-GalNAcAc3-NHCbz

CAS: 1159408-63-5

Ref. 3D-MT184246

Produktinformation

• Name: Tri-b-GalNAcAc3-NHCbz
• Synonyme: Tri-GalNAc (Cbz, peracetylated)Tris-GalNAc (Cbz, peracetylated)Tris-β-GalNAc-Cbz (peracetylated)Tris-GalNAc(OAc)3-CbzTri-β-GalNAc(OAc)3-NHCbz Triantennary β-GalNAc(OAc)3-NHCbz
• Marke: Biosynth
• Beschreibung: This peracetylated tri-b-GalNAcAc3-NHCbz, a triantennary N-acetylgalactosamine (GalNAc) ligand with protected functionalities, serves as a valuable building block for ASGPR-targeted therapies. Its three branches or arms, each ending in a GalNAc sugar, ensure strong binding to hepatocyte ASGPR. However, the key feature lies in its protective groups: acetylated sugars allow for controlled removal to expose reactive sites for conjugation, while the Cbz-protected amine provides stability and can be selectively cleaved to introduce a reactive amine group for further biomolecule attachment, ultimately enabling researchers to tailor Tri-b-GalNAcAc3-NHCbz into customized conjugates for specific therapeutic applications.

Chemische Eigenschaften

• Molekulargewicht: 1,928.04 g/mol
• Formel: C₈₇H₁₃₄N₁₀O₃₈
• Reinheit: Min. 97 Area-%