1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose

CAS: 935658-91-6

Ref. 3D-MT59558

Produktinformation

• Name: 1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose
• Synonyme: 1,2,3,4-Tetra-O-acetyl-6,7-dideoxy-L-galacto-hept-6-ynopyranose5-Alkynylfucose peracetate

Beschreibung

1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose is a per-O-acetylated version of 5-alkynyl-L-fucose, an inhibitor of the cellular fucosylation pathway. 1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose can pass through the eukaryotic cell membrane somewhat better than 5-alkynyl-L-fucose can itself, is deacetylated by cellular esterases and interferes with the biosynthesis of the fucosyl-donor and fucosyltransferase substrate GDP-Fuc, thus reducing fucosylation levels during glycoprotein biosynthesis (Dekkers, 2016).

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 342.3 g/mol
• Formel: C₁₅H₁₈O₉
• Reinheit: Min. 95%
• Farbe/Form: Colorless Clear Liquid