8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine

CAS: 142784-25-6

Ref. 3D-NA04649

Produktinformation

• Name: 8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine
• Synonyme: N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridineN-(D-Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5 -b]pyridine, 2'-Deoxy-8-[(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]guanosine, N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-]pyridine

Beschreibung

8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine (8-APdG) is a mutagen that induces genotoxic effects and mutations in mammalian cells. It has been shown to react with DNA to form covalent complexes and induce point mutations or transversions. 8-APdG has been found in the environment as a result of environmental pollution by polycyclic aromatic hydrocarbons and tobacco smoke. 8-APdG also induces genetic damage in human lymphoblastoid cells in vitro, including mutations at the HPRT locus.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 489.49 g/mol
• Formel: C₂₃H₂₃N₉O₄
• Reinheit: Min. 95%