3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine

Ref. 3D-NA08458

Produktinformation

• Name: 3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine
• Synonyme: 3'-O-Acetyl-2'-deoxy-2'-fluoro-D-thymidine3'-O-Acetyl-2'-fluoro-2'-deoxy-thymidine
• Marke: Biosynth
• Beschreibung: 3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine (3'-O-AFA) is a synthetic, novel antiviral agent that has been shown to inhibit the synthesis of DNA and RNA in cells infected with viruses. 3'-O-AFA is an activator that binds to ribonucleosides and deoxyribonucleosides, which are used in the synthesis of DNA and RNA respectively. The phosphoramidites are then converted into monophosphate or diphosphate nucleotides by the enzyme DNA polymerase. 3'-O-AFA is a modified nucleoside which can be incorporated into viral DNA during replication, inhibiting its production. This drug has also been shown to have anticancer properties against human tumor cells and may be effective against other cancers such as leukemia.

Chemische Eigenschaften

• Molekulargewicht: 302.26 g/mol
• Formel: C₁₂H₁₅FN₂O₆
• Reinheit: Min. 95%