4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

CAS: 141232-24-8

Ref. 3D-NA144556

Produktinformation

• Name: 4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
• Synonyme: 2'-C-Methyl toyocamycin
• Marke: Biosynth
• Beschreibung: 4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (PMPC) is a novel antiviral agent. It is highly active against HIV and has shown to be effective against herpes simplex virus type 1 (HSV1) and HSV type 2 (HSV2). PMPC inhibits the synthesis of viral DNA by phosphorylating a monophosphate residue on the ribonucleoside triphosphate substrate. This prevents the enzyme from adding another phosphate group to the nucleotide sequence, which prevents further DNA synthesis. PMPC also has anticancer properties due to its ability to inhibit cell proliferation by preventing the formation of deoxyribonucleosides and diphosphates.

Chemische Eigenschaften

• Molekulargewicht: 305.29 g/mol
• Formel: C₁₃H₁₅N₅O₄
• Reinheit: Min. 95%