(2R)-2-Hydroxypentanedioic acid

CAS: 13095-47-1

Ref. 3D-NAA09547

Produktinformation

• Name: (2R)-2-Hydroxypentanedioic acid
• Synonyme: D-α-Hydroxyglutaric acid, Pentanedioic acid, 2-hydroxy-, (2R)-, Glutaric acid, 2-hydroxy-, D-, Pentanedioic acid, 2-hydroxy-, (R)-

Beschreibung

(2R)-2-Hydroxypentanedioic acid is a metabolite of 2-hydroxyglutarate that is produced in the metabolism of glucose. This compound has been shown to be elevated in gliomas and may serve as a diagnostic marker for this type of cancer. A mutation in isocitrate dehydrogenase, an enzyme that catalyzes the conversion of isocitrate to alpha-ketoglurate, has been shown to be associated with gliomas. This mutation leads to accumulation of (2R)-2-hydroxypentanedioic acid and increases the risk for this type of cancer. The elevated levels of (2R)-2-hydroxypentanedioic acid can be used as a biomarker for disease activity and diagnosis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 148.11 g/mol
• Formel: C₅H₈O₅
• Reinheit: Min. 95%