4-Pyridinecarboxylic acid, 3-ethyl-, methyl ester

CAS: 13341-16-7

Ref. 3D-NAA34116

Produktinformation

• Name: 4-Pyridinecarboxylic acid, 3-ethyl-, methyl ester

Beschreibung

4-Pyridinecarboxylic acid, 3-ethyl-, methyl ester (PCME) is a synthetic chemical compound that belongs to the group of indole alkaloids. It is used as a precursor in the synthesis of dasycarpidone, an anti-inflammatory drug. PCME is synthesised by the dehydrogenation of 4-(3-ethoxycarbonyl-4-pyridinyl)-2-butanone (1). Protonation of PCM yields the enamine 2 and subsequent reaction with chloroacetyl chloride leads to the desired product. The synthesis of PCME can be described as follows:

Step 1: 4-(3-ethoxycarbonyl-4-pyridinyl)-2-butanone (1) is reacted with sodium methoxide in methanol to yield 4-(3-ethoxycarbonylmethylene)-2-(methylthio)butanal (2

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 165.19 g/mol
• Formel: C₉H₁₁NO₂
• Reinheit: Min. 95%