4-Chlorohippuric acid

CAS: 13450-77-6

Ref. 3D-NAA45077

Produktinformation

• Name: 4-Chlorohippuric acid
• Synonyme: 2-(4-Chlorobenzamido)acetic acid, 2-(4-Chlorobenzamido)aceticacid, 2-[(4-Chlorophenyl)formamido]acetic acid, 4-Chlorobenzoylglycine, 4-Chlorohippuricacid, Glycine, N-(4-chlorobenzoyl)-, Hippuric acid, p-chloro-, N-(4-Chlorobenzoyl)-Glycin, N-(4-Chlorobenzoyl)Glycine, N-(P-Chlorobenzoyl)Glycine, Otava-Bb Bb7210742318, P-Chloro-Hippuricaci, P-Chlorobenzoylglycine, Ro 11-1903, p-Chlorohippuric acid, {[(4-Chlorophenyl)Carbonyl]Amino}Acetate

Beschreibung

4-Chlorohippuric acid is an active analogue of hippuric acid and is metabolized by cytochrome P450. It has a high chemical stability, which makes it a useful substrate for kinetic studies. The metabolism of 4-chlorohippuric acid to the corresponding sulfoxide (4-chloro-3'-sulfoxyhippurate) was found to be dependent on the concentration of rat liver microsomes in vitro and plasma concentrations in vivo. 4-Chlorohippuric acid is excreted mainly as hippuric acid in urine samples from humans and animals. Hippuric acid may also be formed by denaturation of 4-chlorohippurate or by hydrolysis of the amide bond between the two chloro groups.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 213.62 g/mol
• Formel: C₉H₈ClNO₃
• Reinheit: Min. 95%