N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine

CAS: 140712-80-7

Ref. 3D-NB06922

Produktinformation

• Name: N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
• Synonyme: N4-Benzoyl-2'-deoxy-3'-O-DMT-D-cytidineN4-Benzoyl-3'-O-DMT-2'-deoxycytidine
• Marke: Biosynth
• Beschreibung: N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine is a novel nucleoside phosphoramidite with antiviral and anticancer activities. It is synthesized from 2'-deoxycytidine and 4-aminobenzoyl chloride in the presence of tetrazole as a catalyst. The cytidine moiety of N4-benzoyl-2'-deoxy-3'-O-DMT-cytidine is activated by diphosphate, which leads to phosphorylation. This nucleotide has shown potential in inhibiting cancer cell growth and may be used for treatment of leukemia, lymphomas, and myeloma.

Chemische Eigenschaften

• Molekulargewicht: 633.69 g/mol
• Formel: C₃₇H₃₅N₃O₇
• Reinheit: Min. 95%
• InChl: InChI=1S/C37H35N3O7/c1-44-29-17-13-27(14-18-29)37(26-11-7-4-8-12-26,28-15-19-30(45-2)20-16-28)47-31-23-34(46-32(31)24-41)40-22-21-33(39-36(40)43)38-35(42)25-9-5-3-6-10-25/h3-22,31-32,34,41H,23-24H2,1-2H3,(H,38,39,42,43)/t31-,32+,34+/m0/s1
• InChI Key: InChIKey=PTIHHTLJYOOJIY-VOTWKOMSSA-N
• SMILES: COc1ccc(C(O[C@H]2C[C@H](n3ccc(NC(=O)c4ccccc4)nc3=O)O[C@@H]2CO)(c2ccccc2)c2ccc(OC)cc2)cc1