8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium

CAS: 129735-00-8

Ref. 3D-NB13568

Produktinformation

• Name: 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium
• Synonyme: Rp-8-Br-cAMPS
• Marke: Biosynth
• Beschreibung: 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium salt (8-BrAMP) is an activated analog of adenosine that binds to the cyclase enzyme and inhibits its activity. It has been shown to inhibit the production of epidermal growth factor in a model system. 8-BrAMP also blocks the synthesis of cyclic nucleotides by inhibiting cyclic nucleotide phosphodiesterase, which results in increased levels of cAMP. 8-BrAMP has been shown to inhibit HIV infection by acting as a transcription-polymerase chain inhibitor and blocking HIV mRNA synthesis. The drug also inhibits cell lysis by binding to calmodulin and β-catenin.

Chemische Eigenschaften

• Molekulargewicht: 447.16 g/mol
• Formel: C₁₀H₁₁BrN₅O₅PS•Na
• Reinheit: Min. 95%
• Farbe/Form: Powder