2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine

CAS: 130860-11-6

Ref. 3D-NB16514

Produktinformation

• Name: 2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine
• Synonyme: 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-5'-O-(triphenylmethyl)uridine 3'-(O-phenyl carbonothioate)

Beschreibung

2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine (TBS-PTU) is a modified nucleoside that has antiviral activity. TBS-PTU inhibits viral replication by interfering with the synthesis of viral RNA and DNA. The antiviral activity of TBS-PTU is increased in the presence of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. TBS-PTU is used as a building block for DNA synthesis and as a precursor to other modified nucleosides.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 736.95 g/mol
• Formel: C₄₁H₄₄N₂O₇SSi
• Reinheit: Min. 95%