2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethan-1-one

CAS: 663212-40-6

Ref. 3D-NBB21240

Produktinformation

• Name: 2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethan-1-one
• Marke: Biosynth
• Beschreibung: 2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethanone (AET) is a subunit of an ion channel inhibitor. It binds to insect odorant receptors and blocks the activation of the ion channel. AET also blocks the pyridine ring and inhibits heterologous expression in mammalian cells. AET has been shown to be toxic to insects as well as mammals. The toxicity of AET is due to its ability to inhibit ligand binding to co-receptors, which is required for neurotransmitter release.AET has been shown to affect the sensitivity of an insect species towards different concentrations of phenothiazines, which are drugs commonly used in pest control.

Chemische Eigenschaften

• Molekulargewicht: 434.5 g/mol
• Formel: C₂₂H₁₈N₄O₂S₂
• Reinheit: Min. 95%