8-Chloro-2'-deoxyguanosine

CAS: 437715-62-3

Ref. 3D-NC06596

Produktinformation

• Name: 8-Chloro-2'-deoxyguanosine
• Synonyme: 8-Chloro-2'-deoxy-D-guanosine, 8-Chloro-2’-deoxy-D-guanosine

Beschreibung

8-Chloro-2'-deoxyguanosine is a reactive oxygen species that can cause oxidative damage to DNA. This compound is generated by the hypochlorous acid (HOCl) in cells and can be found in human tissues. 8-Chloro-2'-deoxyguanosine can also be generated by the HOCl in diabetic patients, where it has been shown to cause oxidative damage to DNA. 8-Chloro-2'-deoxyguanosine is a product of the reaction between hydrogen peroxide and catalase, and it is activated by HOCl. It has been shown to be carcinogenic in animal models, where it causes DNA damage that leads to cancer.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 301.69 g/mol
• Formel: C₁₀H₁₂ClN₅O₄
• Reinheit: Min. 95%
• Farbe/Form: Powder