8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt

CAS: 93882-12-3

Ref. 3D-NC10429

Produktinformation

• Name: 8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt
• Synonyme: pCPT-cAMP, 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv., 8-(p-Chlorophenylthio)-cAMP sodium salt, Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), monosodium salt, Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), sodium salt (1:1), sodium (4aR,6R,7R,7aS)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl]-9H-purin-9-yl}-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide

Beschreibung

8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt (8-CPT-cAMP) is a cytosolic second messenger that regulates physiological processes. It interacts with the G protein coupled receptor 2-adrenergic receptor, and activates adenylyl cyclase to produce cAMP. 8-CPT-cAMP also induces mitochondrial membrane potential depolarization and Ca2+ release from the endoplasmic reticulum, which leads to cell death. The pro-apoptotic protein Bax is upregulated by 8-CPT-cAMP in cells and contributes to cell death.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 493.79 g/mol
• Formel: C₁₆H₁₄ClN₅NaO₆PS
• Reinheit: Min. 97 Area-%
• Farbe/Form: Powder