2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine

CAS: 120225-75-4

Ref. 3D-NC16518

Produktinformation

• Name: 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
• Synonyme: 1-(6-Amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-b-D-ribofuranuronamide2-Chloro-2',3'-O-isopropylidene adenosine-5'-N-ethylcarboxamide, 1-(6-Amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-β-<span class="text-smallcaps">D</span>-ribofuranuronamide, 2-Chloro-23O-isopropylideneadenosine-5N-ethylcaboxamide, Furo[3,4-d]-1,3-dioxole, β-<span class="text-smallcaps">D</span>-ribofuranuronamide deriv., β-<span class="text-smallcaps">D</span>-Ribofuranuronamide, 1-(6-amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-, Furo[3,4-d]-1,3-dioxole, β-D-ribofuranuronamide deriv., 1-(6-Amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-β-D-ribofuranuronamide, β-D-Ribofuranuronamide, 1-(6-amino-2-chloro-9H-purin-9-yl)-1-deoxy-N-ethyl-2,3-O-(1-methylethylidene)-

Beschreibung

2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine is an antiviral agent that inhibits the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is a synthetic, modified nucleoside. 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine has been shown to be active against human tumor cell lines in vitro and in vivo. The compound inhibits the activity of DNA polymerase and RNA polymerase by competitive inhibition of the enzyme phosphoramidite. 2CECA has also been shown to have anticancer properties as it induces apoptosis in cancer cells.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 382.8 g/mol
• Formel: C₁₅H₁₉ClN₆O₄
• Reinheit: Min. 95%
• InChl: InChI=1S/C15H19ClN6O4/c1-4-18-12(23)8-7-9(26-15(2,3)25-7)13(24-8)22-5-19-6-10(17)20-14(16)21-11(6)22/h5,7-9,13H,4H2,1-3H3,(H,18,23)(H2,17,20,21)
• InChI Key: InChIKey=CHPHKXXDQSHQKC-UHFFFAOYSA-N
• SMILES: CCNC(=O)C1OC(n2cnc3c(N)nc(Cl)nc32)C2OC(C)(C)OC12