R(+)-Baclofen.Hydrochloride

CAS: 63701-55-3

Ref. 3D-NCA70155

Produktinformation

• Name: R(+)-Baclofen.Hydrochloride
• Synonyme: (+)-Baclofen hydrochloride, (R)-4-Amino-3-(4-chlorophenyl)butanoic acid hydrochloride, (R)-4-Amino-3-(4-chlorophenyl)butyric acid hydrochloride, (R)-Baclofen monohydrochloride, Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-, (betaR)-, hydrochloride (1:1), Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride (1:1), (βR)-, Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride, (R)-, Benzenepropanoic acid, β-(aminomethyl)-4-chloro-, hydrochloride, (βR)-, R-Baclofen hydrochloride, d-Baclofen hydrochloride, (3R)-4-Amino-3-(4-chlorophenyl)butanoic acid hydrochloride (1:1)

Beschreibung

R(+)-Baclofen.Hydrochloride is a GABA analogue that stimulates the GABA-benzodiazepine receptor complex and produces antinociception. It has been shown to be effective against diabetic neuropathy in rats, with no observed side effects. R(+)-Baclofen.Hydrochloride is used for the treatment of trigeminal neuralgia, butyric acid induced hyperalgesia and chronic constriction injury in rats. The main mechanism of action of R(+)-Baclofen.Hydrochloride is its ability to activate the benzodiazepine receptor by binding to it, which leads to mitochondrial membrane potential depolarization and an increase in the release of gamma-aminobutyric acid (GABA) from neurons.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 250.12 g/mol
• Formel: C₁₀H₁₃Cl₂NO₂
• Reinheit: Min. 95%