7-Deaza-2'-deoxyguanosine

CAS: 86392-75-8

Ref. 3D-ND02887

Produktinformation

• Name: 7-Deaza-2'-deoxyguanosine
• Synonyme: 7-Deaza-2'-deoxy-D-guanosine, 2-Amino-7-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-7-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,7-dihydro-, 2-Amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, 98: PN: US20050130918 PAGE: 60 claimed sequence, 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-1,7-dihydro-

Beschreibung

7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 266.26 g/mol
• Formel: C₁₁H₁₄N₄O₄
• Reinheit: Min. 95%
• Farbe/Form: White Powder