2'-Deoxy-8-oxo-adenosine

CAS: 62471-63-0

Ref. 3D-ND02928

Produktinformation

• Name: 2'-Deoxy-8-oxo-adenosine
• Synonyme: 2'-Deoxy-7,8-dihydro-8-oxo-adenosine2'-Deoxy-8-hydroxyadenosine

Beschreibung

2'-Deoxy-8-oxo-adenosine is a nucleoside that is a hydrogen bond donor. It is an analogue of adenosine, and has been shown to inhibit the growth of breast cancer cells. 2'-Deoxy-8-oxo-adenosine reacts with the enzyme dATP pyrophosphohydrolase to form 8-oxo-2'-deoxyadenosine, which inhibits mitochondrial DNA synthesis by preventing the incorporation of inorganic phosphate into mitochondrial DNA. This process leads to reduced ATP production, leading to cell death. The reactive properties of 2'-Deoxy-8-oxo-adenosine make it suitable for use as a probe molecule in chemical biology, as well as in biochemical studies on human serum.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 267.25 g/mol
• Formel: C₁₀H₁₃N₅O₄
• Reinheit: Min. 95 Area-%
• Farbe/Form: Powder